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[无症状和有症状HIV感染患者脑脊液和血清中HIV抗原的流行率]

[Prevalence of HIV antigens in cerebrospinal fluid and in serum of patients with both asymptomatic and symptomatic HIV infection].

作者信息

Radkowski M, Laskus T, Kopicz-Kamińska E, Mian M, Babiuch L, Slusarczyk J

机构信息

Zakładu Immunopatologii, Kliniki Nabytych Niedoborów Immunologicznych Instytutu Chorób Zakaźnych i Pasozytniczych, Warszawie.

出版信息

Pol Tyg Lek. 1992;47(36-37):784-6.

PMID:1293560
Abstract

Prevalence of HIV-Ag in both serum and CSF has been determined in 19 HIV infected patients, including 7 patients without any symptoms or only generalized lymphadenopathy, 5 patients with ARC and 7 patients with AIDS. The results have been correlated with clinically evident neurological disorders. HIV-Ag have been detected in 9 out of 12 patients with ARC (AIDS Related Complex) and AIDS. In 8 of them neurological disorders have been present. Out of the remaining 7 patients in only one HIV-Ag has been detected in CSF (p < 025). No correlation between the presence of HIV antigen in CSF and serum has been noted.

摘要

已对19例HIV感染患者的血清和脑脊液中的HIV抗原流行率进行了测定,其中包括7例无症状或仅有全身淋巴结病的患者、5例患艾滋病相关综合征(ARC)的患者和7例患艾滋病的患者。研究结果已与临床明显的神经障碍进行了关联分析。在12例患ARC和艾滋病的患者中,有9例检测到了HIV抗原。其中8例存在神经障碍。在其余7例患者中,仅1例脑脊液中检测到HIV抗原(p<0.025)。未发现脑脊液和血清中HIV抗原的存在之间存在相关性。

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