[取代二苯甲酮的抗心律失常活性脒腙。3. （E）-2-氨基-5-氯二苯甲酮脒腙的异构化]

[Antiarrhythmic active amidinohydrazones of substituted benzophenones. 3. The isomerization of (E)-2-amino-5-chlorobenzophenone amidinohydrazones].

作者信息

Richter P H, Besch A, Albrecht D, Kasbohm K

机构信息

Fachbereich Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.

出版信息

Pharmazie. 1992 Dec;47(12):911-4.

Abstract

The isomerization of the title compound in a preparative scale can be realized by acetylation/deacetylation or by influence of protons in dimethylformamide. The title compound is obtained als main product of the condensation of 2-amino-5-chlorbenzophenone and aminoguanidine if the reaction is carried out in the presence of formaldehyde.

摘要

标题化合物的制备规模异构化可通过乙酰化/脱乙酰化或在二甲基甲酰胺中受质子影响来实现。如果反应在甲醛存在下进行，标题化合物是2-氨基-5-氯二苯甲酮与氨基胍缩合的主要产物。

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