[某些脒腙取代二苯甲酮的抗心律失常作用。1. 新型脒腙和N-苯基脒腙取代二苯甲酮的合成]

[Anti-arrhythmic action of some amidinohydrazone substituted benzophenones. 1. Synthesis of new amidinohydrazone and N-phenylamidinohydrazone substituted benzophenones].

作者信息

Richter P H, Kasbohm K, Besch A, Hagen A

机构信息

Fachbereich Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.

出版信息

Pharmazie. 1992 Oct;47(10):758-64.

Abstract

The title compounds are synthesized as a rule by condensation of substituted benzophenones and derivatives of aminoguanidine in the presence of up to 2.5 moles of an anorganic acid. They can be obtained alternatively via corresponding hydrazones, thiosemicarbazones or methylthiothiocarbonylhydrazones.

摘要

通常情况下，标题化合物是通过在至多2.5摩尔无机酸存在下，使取代二苯甲酮与氨基胍衍生物缩合来合成的。它们也可以通过相应的腙、硫代半卡巴腙或甲硫代硫代羰基腙来制备。

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