Schleuder M, Richter P H, Keckeis A, Jira T
Fachbereich Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.
Pharmazie. 1993 Jan;48(1):33-7.
The aqueous solution of the title compound can be used for injection for one year if it is stored at room temperature and under light protection. Under these conditions 8% of the E-isomer are produced. The reaction is reversible at day light. Red coloured products of decomposition are formed by long lasting influence of light. At higher temperatures or at sterilisation several products of decomposition are formed which structure is elucidated. For these decomposition a scheme is proposed.
如果标题化合物的水溶液在室温下避光保存,可用于注射一年。在这些条件下会产生8%的E-异构体。该反应在日光下是可逆的。长时间光照会形成红色分解产物。在较高温度或灭菌时会形成几种分解产物,其结构已被阐明。针对这些分解提出了一个方案。