Doehring-Schwerdtfeger E, Kaiser C, Schlake J, Abdel-Rahim I M, Mohamed-Ali Q, Richter J, Franke D, Kardorff R, Elsheikh M, Ehrich J H
Institute for Medical Parasitology, University of Bonn, Germany.
Trop Med Parasitol. 1992 Dec;43(4):245-8.
In order to compare clinical versus ultrasound based diagnosis of Schistosoma mansoni induced periportal fibrosis (pF) 536 infected Sudanese schoolchildren underwent clinical and sonographical examination. A liver exceeding 3 cm in sternal line and a palpable spleen were considered pathological. Ultrasound criteria for age dependent organometry of a Central European cohort were used as reference. Based on clinical criteria 190 children (35.4%) had hepatomegaly, whereas according to ultrasound results the rate was only 11.4%. Splenomegaly was detected in 77 cases (14.4%) by clinical means, but in 196 by ultrasound (36.6%). The sensitivity of clinical parameters as indication of pF was around 50%. Results for ultrasound detected organomegaly were only slightly better. It was concluded that assessment of liver and spleen sizes was of limited value as an indication for pF and that a considerable discrepancy existed between clinical and ultrasound based assessment of hepato- and splenomegaly.
为了比较基于临床诊断与超声诊断曼氏血吸虫所致门周纤维化（pF）的差异，对536名受感染的苏丹学童进行了临床和超声检查。胸骨线处肝脏超过3厘米且可触及脾脏被视为病理状态。以中欧队列中年龄相关器官测量的超声标准作为参考。根据临床标准，190名儿童（35.4%）有肝肿大，而根据超声结果，这一比例仅为11.4%。通过临床检查发现77例（14.4%）有脾肿大，但超声检查发现196例（36.6%）有脾肿大。临床参数作为pF指标的敏感性约为50%。超声检测到的器官肿大结果仅略好一些。得出的结论是，肝脏和脾脏大小的评估作为pF的指标价值有限，并且基于临床和超声的肝肿大及脾肿大评估之间存在相当大的差异。
