Popuchiev V V, Yakovleva N D, Konoplyannikov A G, Kvetnoi I M, Kita K, Kita I
Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk.
Bull Exp Biol Med. 2003 Jun;135(6):603-7. doi: 10.1023/a:1025402007545.
Electron microscopy showed that whole-body gamma-irradiation in sublethal doses led to the appearance of injuries in pinealocytes, glial cells, and vessels of the pineal gland in rats. Limitation of the nonspecific effect of gamma-irradiation via inhibition of adrenocortical function with metopirone in physiological doses reduced the radiation-induced ultrastructural damage to the pineal gland.
电子显微镜检查显示，亚致死剂量的全身γ射线照射导致大鼠松果体细胞、神经胶质细胞和松果体血管出现损伤。通过生理剂量的美替拉酮抑制肾上腺皮质功能来限制γ射线照射的非特异性效应，可减少辐射诱导的松果体超微结构损伤。
