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丘系和非丘系听觉丘脑的功能组织

Functional organization of lemniscal and nonlemniscal auditory thalamus.

作者信息

Hu B

机构信息

Department of Clinical Neurosciences and Neuroscience Research Group, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1, Canada.

出版信息

Exp Brain Res. 2003 Dec;153(4):543-9. doi: 10.1007/s00221-003-1611-5. Epub 2003 Aug 23.

DOI:10.1007/s00221-003-1611-5
PMID:12937877
Abstract

Thalamic nuclei of the mammalian auditory system exhibit remarkable parallelism in their anatomical pathways and the patterns of synaptic signalling. This has led to the theory that lemniscal, or core thalamocortical projection, carries tonotopically organized and auditory specific information whereas the nonlemniscal thalamocortical pathway forms part of an integrative system that plays an important role in polysensory integration, temporal pattern recognition, and certain forms of learning. Recent experimental evidence derived from molecular, cellular and behavioural studies indeed supports the conjecture that lemniscal and nonlemniscal pathways are involved in distinctive auditory functions.

摘要

哺乳动物听觉系统的丘脑核在其解剖学通路和突触信号模式上表现出显著的平行性。这导致了一种理论,即lemniscal(或核心丘脑皮质投射)携带音调拓扑组织化的听觉特定信息,而非lemniscal丘脑皮质通路则构成了一个整合系统的一部分,该系统在多感觉整合、时间模式识别和某些形式的学习中发挥重要作用。最近来自分子、细胞和行为研究的实验证据确实支持了lemniscal和非lemniscal通路参与不同听觉功能的推测。

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Whisker maps of neuronal subclasses of the rat ventral posterior medial thalamus, identified by whole-cell voltage recording and morphological reconstruction.通过全细胞膜片钳记录和形态学重建鉴定的大鼠腹后内侧丘脑神经元亚类的触须图。
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Sounds, signals and space maps.
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Multiple Concurrent Predictions Inform Prediction Error in the Human Auditory Pathway.多模态并发预测可反映人类听觉通路中的预测误差。
J Neurosci. 2024 Jan 3;44(1):e2219222023. doi: 10.1523/JNEUROSCI.2219-22.2023.
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Mixed representations of sound and action in the auditory midbrain.听觉中脑中声音与动作的混合表征。
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