Liu F, Wei Y, Yang X Z, Li F G, Hu J, Cheng R F
Department of Pharmacology, Xin jing Medical College, Urümuqi.
Yao Xue Xue Bao. 1992;27(10):785-7.
Safflower yellow (SY) is a mixture of chalconoid compounds extracted from Carthamus tinctorius L. Ig SY 1-2 g.kg-1.d-1 lowered the blood pressure of spontaneously hypertensive rats (SHR), for about 1.86-3.86 kPa. Five weeks after administration of SY, the plasma renin activity and angiotensin II level diminished in the SHR experimental groups. These suggest that the decrease of blood pressure is mediated by the renin-angiotensin system.
红花黄色素(SY)是从红花中提取的查耳酮类化合物的混合物。若给予SY 1-2克/千克/天,可使自发性高血压大鼠(SHR)的血压降低约1.86-3.86千帕。给予SY五周后,SHR实验组的血浆肾素活性和血管紧张素II水平降低。这些表明血压降低是由肾素-血管紧张素系统介导的。