Pan X P
Department of Pharmacy, Tongyi Medical University, Wuhan.
Yao Xue Xue Bao. 1992;27(10):788-91.
A new phenolic dauricine-type alkaloid together with the know dauricine were isolated from the rhizoma of Menispermum dauricum DC cultivated in Xianning district, Hubei province. Dauricine was obtained as the major alkaloid and was confirmed by comparison with authentic sample. The new alkaloid is an unstable white powder: Based on spectrometric analysis (UV, IR, FAB-MS and 1HNMR) and N-methylation which offered dauricine dimethiodide (V), the structure was elucidated as RR, N-desmethyldauricine (II), which was isolated for the first time from nature.
从湖北咸宁地区种植的蝙蝠葛根茎中分离得到一种新的酚性蝙蝠葛碱型生物碱以及已知的蝙蝠葛碱。蝙蝠葛碱作为主要生物碱获得，并通过与标准品比较得以确认。该新生物碱为不稳定的白色粉末：基于光谱分析（紫外、红外、快原子轰击质谱和核磁共振氢谱）以及生成蝙蝠葛碱二甲基碘化物（V）的N-甲基化反应，其结构被鉴定为RR，N-去甲基蝙蝠葛碱（II），这是首次从自然界中分离得到。
