Olafsdottir E, Gilja O H, Tefera S, Fluge G, Berstad A
Dept. of Paediatrics and Institute of Medicine, University of Bergen, Norway.
Scand J Gastroenterol. 2003 Aug;38(8):819-25. doi: 10.1080/00365520310003480.
Using two-dimensional (2D) ultrasonography, we previously found indications of impaired adaptive relaxation of the proximal stomach in children with recurrent abdominal pain (RAP). In the present study, we applied a new three-dimensional (3D) ultrasonographic method to investigate intragastric volumes and distribution of a liquid meal in another group of children with RAP.
Twenty patients with RAP (age 10-15 years) and 20 healthy subjects (age 11-15 years) underwent ultrasonographic measurements of the stomach. A position sensor was used based on magnetic scanhead tracking for acquisition of 3D images after a liquid meal. The children scored abdominal symptoms before and after the meal.
Expressed as a fraction of ingested volume, the patients had a smaller volume of the proximal stomach and a larger antral volume at 2 min postprandially compared to healthy subjects (P = 0.03 and P = 0.001, respectively). The patients also showed a decreased proximal to distal gastric volume ratio at 2 min postprandially (P = 0.001). Patients experienced more pain in response to the meal than healthy subjects (P = 0.04), but there was no correlation between pain and proximal or distal gastric volumes.
RAP in children may be associated with an early intragastric maldistribution of a meal.
我们之前使用二维超声检查发现，复发性腹痛（RAP）患儿近端胃适应性舒张受损。在本研究中，我们应用一种新的三维超声检查方法，对另一组RAP患儿胃内液体餐的体积和分布进行研究。
20例RAP患儿（年龄10 - 15岁）和20名健康受试者（年龄11 - 15岁）接受了胃部超声检查。液体餐后，基于磁探头跟踪使用位置传感器获取三维图像。患儿在餐前和餐后对腹部症状进行评分。
以摄入体积的分数表示，与健康受试者相比，患儿在餐后2分钟时近端胃体积较小，胃窦体积较大（分别为P = 0.03和P = 0.001）。患儿在餐后2分钟时近端与远端胃体积比也降低（P = 0.001）。与健康受试者相比，患儿对进食的疼痛反应更多（P = 0.04），但疼痛与近端或远端胃体积之间无相关性。
儿童RAP可能与进食后早期胃内分布异常有关。
