Tefera S, Gilja O H, Olafsdottir E, Hausken T, Hatlebakk J G, Berstad A
Division of Gastroenterology, Institute of Medicine, Haukeland Hospital, University of Bergen, Norway.
Gut. 2002 Feb;50(2):153-8. doi: 10.1136/gut.50.2.153.
Our aim was to study intragastric volume and distribution of a liquid meal in patients with reflux oesophagitis using three dimensional ultrasonography.
Twenty patients and 20 healthy controls underwent ultrasonographic measurements of the stomach using a position sensor based on magnetic scanhead tracking for acquisition of three dimensional images. In vivo accuracy of the method was evaluated by scanning a soup filled barostat bag positioned in the proximal stomach of six healthy subjects.
In the volume range 100-700 ml, our three dimensional system showed excellent correlation (r=0.99) between estimated and true volumes (limits of agreement -3.4 to 11.0 ml) and a low interobserver variation (limits of agreement -10.9 to 6.7 ml). After ingestion of a 500 ml meat soup meal, patients with reflux oesophagitis revealed a larger volume of the total and proximal stomach at two and 10 minutes (p=0.05; p=0.01, respectively), and an increased proximal/distal intragastric volume ratio at 10 minutes (p=0.04). Patients also experienced more epigastric fullness than controls (p=0.0006).
The present three dimensional ultrasound system showed excellent agreement with true volumes and low interobserver variation. Soon after a liquid meal, patients with reflux oesophagitis have abnormal pooling of the ingested liquid in the proximal stomach.
我们的目的是使用三维超声研究反流性食管炎患者胃内液体餐的体积及分布情况。
20例患者和20名健康对照者接受了基于磁探头跟踪的位置传感器进行的胃部超声测量，以获取三维图像。通过对放置在6名健康受试者近端胃内的充满汤的恒压器袋进行扫描，评估该方法在体内的准确性。
在100 - 700毫升的体积范围内，我们的三维系统显示估计体积与实际体积之间具有极佳的相关性（r = 0.99）（一致性界限为 - 3.4至11.0毫升），且观察者间差异较小（一致性界限为 - 10.9至6.7毫升）。摄入500毫升肉汤餐后，反流性食管炎患者在2分钟和10分钟时胃总容积和近端胃容积更大（分别为p = 0.05；p = 0.01），且在10分钟时近端/远端胃内体积比增加（p = 0.04）。患者也比对照组更易感到上腹部饱胀（p = 0.0006）。
目前的三维超声系统与实际体积显示出极佳的一致性，且观察者间差异较小。液体餐后不久，反流性食管炎患者摄入的液体在近端胃内出现异常潴留。
