Gene transcription in HIV infection.
作者信息
Wu Yuntao, Marsh Jon W
机构信息
Laboratory of Molecular Biology, National Institute of Mental Health, 36 Convent Drive, Bethesda, MD 20892-4034, USA.
出版信息
Microbes Infect. 2003 Sep;5(11):1023-7. doi: 10.1016/s1286-4579(03)00187-4.
Abstract
Transcription from the HIV genome is regulated by the 5' long-terminal-repeat viral promoter as well as regulatory proteins, especially Tat and Rev. Both the promoter activity and the function of regulatory proteins require the activity of cellular components, thus the virus remains highly dependent on the metabolic state of the cell. HIV also possesses the unusual capacity to transcribe from non-integrated DNA.
摘要
Zotero 插件