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患者自控静脉镇痛是接受胃旁路手术的病态肥胖患者可接受的疼痛管理策略。与硬膜外镇痛的回顾性比较。

Patient controlled i.v. analgesia is an acceptable pain management strategy in morbidly obese patients undergoing gastric bypass surgery. A retrospective comparison with epidural analgesia.

作者信息

Charghi Roshanak, Backman Steven, Christou Nicolas, Rouah Fabrice, Schricker Thomas

机构信息

Department of Anesthesia, Royal Victoria Hospital, Montreal, Quebec, Canada.

出版信息

Can J Anaesth. 2003 Aug-Sep;50(7):672-8. doi: 10.1007/BF03018709.

Abstract

PURPOSE

To examine the hypothesis that pain treatment with patient controlled analgesia (PCA) using iv morphine is a suitable and safe alternative to epidural analgesia in morbidly obese patients undergoing gastric bypass surgery. We retrospectively compared the postoperative periods in all patients undergoing this procedure in our institution between November 1999 and November 2001.

METHODS

According to their perioperative pain treatment, patients were assigned to a PCA group (with iv morphine) or an epidural analgesia group, in which patients received either intermittent doses of morphine or continuous infusions of bupivacaine/fentanyl. Study endpoints included quality of pain control, incidence of cardiovascular and respiratory complications, analgesia related side effects, time to ambulation and first flatus, length of hospital stay, and wound infections.

RESULTS

Data from 86 patients were analyzed with 40 patients in the PCA group and 46 patients in the epidural group. Groups were similar with respect to age, body mass index, and gender. The type of analgesia did not affect the quality of pain control at rest, the frequency of nausea and pruritus, the time to ambulation and return of gastrointestinal function, and the length of hospital stay. Patients receiving epidural analgesia had a greater risk of wound infection than subjects with PCA (epidural group: 39%, PCA group: 15%, P = 0.01).

CONCLUSION

We conclude that in grossly obese patients undergoing gastric bypass surgery PCA with iv morphine is an acceptable strategy for pain management and may confer some advantages when compared to epidural analgesia.

摘要

目的

检验以下假设:对于接受胃旁路手术的病态肥胖患者,使用静脉注射吗啡的患者自控镇痛(PCA)是硬膜外镇痛的一种合适且安全的替代方法。我们回顾性比较了1999年11月至2001年11月在我院接受该手术的所有患者的术后情况。

方法

根据围手术期疼痛治疗方法,将患者分为PCA组(使用静脉注射吗啡)或硬膜外镇痛组,硬膜外镇痛组患者接受间断剂量吗啡或布比卡因/芬太尼持续输注。研究终点包括疼痛控制质量、心血管和呼吸系统并发症发生率、镇痛相关副作用、下床活动和首次排气时间、住院时间以及伤口感染情况。

结果

分析了86例患者的数据,其中PCA组40例,硬膜外组46例。两组在年龄、体重指数和性别方面相似。镇痛类型不影响静息时的疼痛控制质量、恶心和瘙痒的发生率、下床活动和胃肠功能恢复时间以及住院时间。接受硬膜外镇痛的患者比PCA组患者发生伤口感染的风险更高(硬膜外组:39%,PCA组:15%,P = 0.01)。

结论

我们得出结论,对于接受胃旁路手术的极度肥胖患者,静脉注射吗啡的PCA是一种可接受的疼痛管理策略,与硬膜外镇痛相比可能具有一些优势。

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