Girerd X, Mounier-Vehier C, Fauvel J P, Marquand A, Babici D, Hanon O
Service d'endocrinologie métabolisme, hôpital Pitié-Salpêtrière, 83, bd de l'Hôpital, 75013 Paris.
Arch Mal Coeur Vaiss. 2003 Jul-Aug;96(7-8):758-62.
Decrease in sexual desire is a disturbance affecting treated hypertensive subjects of both sexes. In contrast with erection problems, this abnormality has rarely been studied in hypertensives treated with antihypertensive drugs.
To evaluate, using a self-administered questionnaire, the prevalence of sexual disturbance (decrease in sexual desire) in treated hypertensive subjects and to determine the management of these troubles.
In 428 hypertensive subjects, living in France and referred to hypertension specialists, a self-administered questionnaire evaluating the quality of sexual activity was given before the consultation. Nine specific questions focused on the quality of sexual function for the last 6 months in men or women (interest for sexuality, sexual desire, sexual pleasure). Secondly, the doctors were questioned about their management of these sexual disturbances.
In this population of treated hypertensives, including 270 men and 158 women, with a blood pressure level of 139 +/- 20/84 +/- 13 mmHg, a decrease in sexual desire was reported by 47% of men (127/270) and 48% of women (76/158). Sexual disturbance was related to antihypertensive drugs in 46% of cases (93/203), more often in men (59% [75/127]) than in women (24%, [18/76]), p < 0.001). In subjects with sexual disturbance, a specific medical management has been proposed in 35% of cases (71/203), especially in men (in 46% of cases [58/127], and consisted in a specialized consultation for 34% (43/127) and/or the prescription of Sildenafil for 20% (26/127). In women, the lack of management of these troubles was more often observed than in men (82% vs 54%; p < 0.01). Modifications of antihypertensive treatments were rarely observed in 15% of cases (30/203) comparatively in men and women.
Men and women with treated hypertension are at "high risk" of sexual disturbance. Management of sexual dysfunction in these subjects concerns only 35% of cases, especially men, including specific treatments and/or consultations, but changing in antihypertensive drugs still remains rare.
性欲减退是一种影响接受治疗的男女高血压患者的病症。与勃起功能障碍不同，这种异常情况在接受抗高血压药物治疗的高血压患者中很少得到研究。
使用一份自行填写的问卷，评估接受治疗的高血压患者中性功能障碍（性欲减退）的患病率，并确定对这些问题的处理方式。
在法国，428名转诊至高血压专科医生处的高血压患者在就诊前填写了一份评估性活动质量的自行填写问卷。九个具体问题聚焦于男性或女性过去6个月的性功能质量（对性的兴趣、性欲、性快感）。其次，询问医生对这些性功能障碍的处理方式。
在这组接受治疗的高血压患者中，包括270名男性和158名女性，血压水平为139±20/84±13 mmHg，47%的男性（127/270）和48%的女性（76/158）报告有性欲减退。46%的病例（93/203）中的性功能障碍与抗高血压药物有关，男性（59%[75/127]）比女性（24%，[18/76]）更常见，p<0.001）。在性功能障碍患者中，35%的病例（71/203）提出了特定的医学处理建议，尤其是男性（46%的病例[58/127]），其中34%（43/127）包括专科会诊和/或20%（26/127）开具西地那非。在女性中，这些问题未得到处理的情况比男性更常见（82%对54%；p<0.01）。在15%的病例（30/203）中，与男性和女性相比，很少观察到抗高血压治疗的调整。
接受治疗的高血压男性和女性存在性功能障碍的“高风险”。这些患者中性功能障碍的处理仅涉及35%的病例，尤其是男性，包括特定治疗和/或会诊，但更换抗高血压药物的情况仍然很少见。
