Mather Melissa L, Baldock Clive
Centre for Medical, Health and Environmental Physics, Queensland University of Technology, Brisbane, Australia.
Med Phys. 2003 Aug;30(8):2140-8. doi: 10.1118/1.1590751.
A novel imaging system for investigation of absorbed dose distributions in radiotherapy polymer gel dosimeters using ultrasound is introduced. A prototype transmission ultrasound computed tomography (UCT) imaging system is developed and evaluated. The imaging capabilities of the system are assessed through investigation of an irradiated polyacrylamide gel test phantom. Images based on transmitted signal amplitude and time of flight (TOF) of the ultrasonic signal through the phantom are reconstructed using a filtered backprojection technique. In general, the reconstruction of the square field in the TOF image was superior to the transmission image, however, transmission images displayed superior contrast to TOF images. The image quality achieved with this prototype system is promising and could be significantly enhanced through improvements, in particular through the development of more sophisticated experimental equipment. It is concluded that UCT is a viable technique for imaging absorbed dose distributions in polymer gel dosimeters and investigations are continuing to further improve the system.
介绍了一种用于研究放疗聚合物凝胶剂量计中吸收剂量分布的新型超声成像系统。开发并评估了一种原型透射超声计算机断层扫描(UCT)成像系统。通过对辐照过的聚丙烯酰胺凝胶测试体模进行研究,评估了该系统的成像能力。利用滤波反投影技术重建基于超声信号穿过体模的透射信号幅度和飞行时间(TOF)的图像。总体而言,TOF图像中方形野的重建优于透射图像,然而,透射图像显示出比TOF图像更好的对比度。该原型系统所实现的图像质量很有前景,通过改进,特别是开发更先进的实验设备,图像质量可以得到显著提高。得出的结论是,UCT是一种用于聚合物凝胶剂量计中吸收剂量分布成像的可行技术,并且正在继续进行研究以进一步改进该系统。