Xua Y, Wuu Cheng-Shie, Maryanski Marek J
Department of Radiation Oncology, Columbia University, New York, New York 10032, USA.
Med Phys. 2003 Aug;30(8):2257-63. doi: 10.1118/1.1593837.
A method for determining the gel sensitivity that is necessary for obtaining optimal image contrast in optical CT scanning of gel dosimeters is presented. The effective dynamic range of the OCTOPUS-ONE research scanner (MGS Research, Inc., Madison, CT) is analyzed. Optical density increments for selected straight-line paths across a gel cylinder to be scanned are calculated based on the optical properties of the polymer gel and the dose distribution from a commercial treatment planning system (Cadplan, Varian Corporation, Palo Alto, CA). Maximum optical density increment across the entire gel is obtained by searching the gel cylinder over a set of transverse planes at different rotational angles. The application of this quantity as a criterion for optimizing the quality of the optical CT scanning is demonstrated through dose verification of two representative treatment plans. When the MU dependence of the dose distribution for a treatment plan is linear, as is the case for static field irradiation, it is possible to scale the treatment plan such that the intensity variation of the signals received by the photodetector spans its entire dynamic range. For treatment plans that are possibly nonlinear, IMRT plans, for example, modification of the sensitivity of the gel material is necessary for the high-dose signals to be collected at a certain signal-to-noise ratio. Results obtained using the optimized CT scanning approach are compared with those from the treatment planning system and the film measurement.
本文提出了一种确定凝胶敏感度的方法,该敏感度对于在凝胶剂量计的光学CT扫描中获得最佳图像对比度是必要的。分析了OCTOPUS-ONE研究型扫描仪(MGS Research公司,麦迪逊,康涅狄格州)的有效动态范围。基于聚合物凝胶的光学特性和来自商业治疗计划系统(Cadplan,瓦里安公司,帕洛阿尔托,加利福尼亚州)的剂量分布,计算穿过待扫描凝胶圆柱体的选定直线路径的光密度增量。通过在不同旋转角度的一组横向平面上搜索凝胶圆柱体,获得整个凝胶上的最大光密度增量。通过对两个代表性治疗计划的剂量验证,证明了将该量用作优化光学CT扫描质量的标准的应用。当治疗计划的剂量分布对MU的依赖性呈线性时,如静态场照射的情况,有可能调整治疗计划,使得光电探测器接收到的信号强度变化跨越其整个动态范围。对于可能是非线性的治疗计划,例如IMRT计划,为了以一定的信噪比收集高剂量信号,需要改变凝胶材料的敏感度。将使用优化的CT扫描方法获得的结果与来自治疗计划系统和胶片测量的结果进行比较。