Lee Shi Nae, Cho Min Sun, Koo Heasoo, Han Woon Sup
Department of Pathology, Medical College, Ewha Womans University, Seoul, South Korea.
Arch Pathol Lab Med. 2003 Sep;127(9):e378-81. doi: 10.5858/2003-127-e378-EHTACR.
Ectopic hamartomatous thymoma is a rare benign tumor that consists of spindle, epithelial, and adipose cell elements. We present a case of this lesion arising in the supraclavicular region of a 59-year-old man, including the characteristic immunohistochemical and ultrastructural findings. DNA flow cytometry revealed diploidy with a low proliferation index (6.73%). The tumor contained CD99+ lymphocytes; CD99 (MIC2) can serve as a useful marker of immature T cells. These findings suggest that ectopic hamartomatous thymoma may develop from the third branchial pouch or thymic anlage.
异位错构瘤性胸腺瘤是一种罕见的良性肿瘤，由梭形细胞、上皮细胞和脂肪细胞成分组成。我们报告了一例发生在一名59岁男性锁骨上区域的该病变病例，包括其特征性的免疫组织化学和超微结构表现。DNA流式细胞术显示为二倍体，增殖指数较低（6.73%）。肿瘤含有CD99+淋巴细胞；CD99（MIC2）可作为未成熟T细胞的有用标志物。这些发现提示异位错构瘤性胸腺瘤可能起源于第三鳃囊或胸腺原基。
