Paavilainen Petri, Mikkonen Mikko, Kilpeläinen Markku, Lehtinen Reia, Saarela Miiamaaria, Tapola Lauri
Helsinki Brain Research Center, Cognitive Brain Research Unit, Helsinki, Finland.
Neurosci Lett. 2003 Oct 2;349(2):79-82. doi: 10.1016/s0304-3940(03)00787-0.
The auditory sensory-memory mechanisms in the human brain were investigated using the mismatch negativity (MMN) component of the event-related potential. MMNs were recorded to stimuli deviating from the repetitive standard stimuli simultaneously either in one or two features (frequency, intensity). If the processing of these two features is independent of each other, the MMN to the double deviant should equal the sum of the MMNs elicited by the corresponding single deviants. The double-deviant MMNs were found to be additive at the electrode sites below the Sylvian fissure but not at the frontal scalp areas. The results suggest that the temporal subcomponent of MMN is additive whereas the frontal is non-additive. The pattern of results was similar in ignore and attend conditions, suggesting that the components were not attentionally modulated.
利用事件相关电位的失配负波（MMN）成分，对人类大脑中的听觉感觉记忆机制进行了研究。记录了对在频率、强度这一个或两个特征上同时偏离重复标准刺激的刺激所产生的MMN。如果这两个特征的处理相互独立，那么对双重偏差刺激的MMN应该等于由相应单一偏差刺激所引发的MMN之和。结果发现，在颞叶沟裂下方的电极部位，双重偏差MMN具有可加性，但在额部头皮区域则不然。结果表明，MMN的颞叶子成分具有可加性，而额叶子成分则不具有可加性。在忽略和注意条件下，结果模式相似，这表明这些成分不受注意力调节。
