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一种ICE模式结晶形成。

An ICE pattern crystallizes.

作者信息

Spahn Laura, Barlow Denise P

出版信息

Nat Genet. 2003 Sep;35(1):11-2. doi: 10.1038/ng0903-11.

DOI:10.1038/ng0903-11
PMID:12947402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2847178/
Abstract

Identification of a new imprinting control element (ICE) on mouse chromosome 12 brings the total to five. Common features of imprinting mechanisms suggest a general model of ICE function.

摘要

在小鼠12号染色体上鉴定出一个新的印记控制元件(ICE),使得此类元件总数达到了五个。印记机制的共同特征提示了一个ICE功能的通用模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f222/2847178/0063213e35e5/ukmss-29292-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f222/2847178/0063213e35e5/ukmss-29292-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f222/2847178/0063213e35e5/ukmss-29292-f0001.jpg

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Imprinted silencing of Slc22a2 and Slc22a3 does not need transcriptional overlap between Igf2r and Air.Slc22a2和Slc22a3的印记沉默不需要Igf2r和Air之间的转录重叠。
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