Asherson R A, Ames D, Coltart J, Byrne C, Hughes G R
Department of Rheumatology, St. Thomas' Hospital, London, UK.
J Rheumatol. 1992 Dec;19(12):1973-7.
Two patients, both women, one with "lupus-like" disease, age 51 years, the other a 45-year-old with systemic lupus erythematosus (SLE), developed symptoms and echocardiographic signs of hypertrophic cardiomyopathy. One patient had a family history of sudden maternal death. Neither patient had a history of sustained hypertension and there were no significant valvular lesions detectable to account for the septal and ventricular hypertrophy. The association of SLE or any related condition with hypertrophic cardiomyopathy has not been recorded. In one patient the question of a hereditary cardiomyopathy remains a possibility. The diagnosis of the condition was based on clinical and echocardiographic grounds alone. No endomyocardial biopsies were performed.
两名患者均为女性，一名51岁，患有“狼疮样”疾病，另一名45岁，患有系统性红斑狼疮（SLE），她们出现了肥厚型心肌病的症状和超声心动图体征。一名患者有母亲猝死的家族史。两名患者均无持续性高血压病史，且未检测到明显的瓣膜病变来解释室间隔和心室肥厚。SLE或任何相关疾病与肥厚型心肌病的关联尚未见报道。在一名患者中，遗传性心肌病的可能性仍然存在。该疾病的诊断仅基于临床和超声心动图依据。未进行心内膜活检。
