Nathe Ana R, Frank Loren M
Program in Neuroscience, Boston University, Boston, MA 02155, USA.
Neuron. 2003 Aug 28;39(5):730-1. doi: 10.1016/s0896-6273(03)00537-3.
The formation of spatial memories is believed to depend on long-term potentiation (LTP) of synapses within the hippocampal network. In this issue of Neuron, Dragoi et al. demonstrate that LTP can cause changes in the hippocampal representation of space without disrupting network dynamics. These results help define the elusive relationship between cellular-level synaptic plasticity and systems-level neural coding.
空间记忆的形成被认为依赖于海马体网络内突触的长时程增强（LTP）。在本期《神经元》杂志中，德拉戈伊等人证明，长时程增强可导致海马体空间表征的变化，而不会破坏网络动态。这些结果有助于明确细胞水平的突触可塑性与系统水平的神经编码之间难以捉摸的关系。
