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皮肤松弛症与莱姆病:是否存在发病机制上的关联?

Anetoderma and borreliosis: is there a pathogenetic relationship?

作者信息

Hofer Thomas, Goldenberger Daniel, Itin Peter H

出版信息

Eur J Dermatol. 2003 Jul-Aug;13(4):399-401.

PMID:12948924
Abstract

A 32-year-old man simultaneously developed anetoderma and acrodermatitis chronica atrophicans on his left arm and showed a positive serology for borreliosis with ELISA and Western Blot tests. In addition, a 45 year-old man is presented with anetoderma without any associated systemic or cutaneous diseases, with B. afzelii confirmed as a singular causality through serology (ELISA, Western Blot) and amplification of B. afzelii-specific DNA from the skin by PCR. These two observations highly suggest that anetoderma can be the result of an infection with B. afzelii. We conclude that in patients with anetoderma a serological investigation for Borreliosis should be performed.

摘要

一名32岁男性左臂同时出现了皮肤松弛症和慢性萎缩性肢皮炎,酶联免疫吸附测定(ELISA)和蛋白质印迹法检测显示其血清学检测莱姆病呈阳性。此外,一名45岁男性出现皮肤松弛症,无任何相关的全身性或皮肤性疾病,通过血清学检测(ELISA、蛋白质印迹法)以及利用聚合酶链反应(PCR)从皮肤中扩增出阿氏疏螺旋体特异性DNA,证实阿氏疏螺旋体是唯一病因。这两项观察结果强烈表明,皮肤松弛症可能是由阿氏疏螺旋体感染所致。我们得出结论,对于患有皮肤松弛症的患者,应进行莱姆病的血清学调查。

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Anetoderma and borreliosis: is there a pathogenetic relationship?皮肤松弛症与莱姆病:是否存在发病机制上的关联?
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Open Access Maced J Med Sci. 2019 Aug 19;7(18):3093-3095. doi: 10.3889/oamjms.2019.560. eCollection 2019 Sep 30.
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Borrelia burgdorferi Infections in the United States.美国的伯氏疏螺旋体感染
J Clin Aesthet Dermatol. 2012 Aug;5(8):18-28.