Taga Michiko E, Bassler Bonnie L
Department of Molecular Biology, Princeton University, Princeton, NJ 08544-1014, USA.
Proc Natl Acad Sci U S A. 2003 Nov 25;100 Suppl 2(Suppl 2):14549-54. doi: 10.1073/pnas.1934514100. Epub 2003 Aug 29.
Cell-cell communication in bacteria is accomplished through the exchange of chemical signal molecules called autoinducers. This process, called quorum sensing, allows bacteria to monitor their environment for the presence of other bacteria and to respond to fluctuations in the number and/or species present by altering particular behaviors. Most quorum-sensing systems are species- or group-specific, which presumably prevents confusion in mixed-species environments. However, some quorum-sensing circuits control behaviors that involve interactions among bacterial species. These quorum-sensing circuits can involve both intra- and interspecies communication mechanisms. Finally, anti-quorumsensing strategies are present in both bacteria and eukaryotes, and these are apparently designed to combat bacteria that rely on cell-cell communication for the successful adaptation to particular niches.
细菌中的细胞间通讯是通过称为自诱导物的化学信号分子的交换来实现的。这个过程称为群体感应,它使细菌能够监测其周围环境中其他细菌的存在,并通过改变特定行为来响应细菌数量和/或种类的波动。大多数群体感应系统具有物种特异性或群体特异性,这大概可以防止在混合物种环境中产生混淆。然而,一些群体感应回路控制着涉及细菌物种间相互作用的行为。这些群体感应回路可能涉及种内和种间通讯机制。最后,细菌和真核生物中都存在群体感应抑制策略,这些策略显然是为了对抗那些依靠细胞间通讯来成功适应特定生态位的细菌。