Akt helps stem cells heal the heart.

Suppr

超能文献

作者信息

Koç Omer N, Gerson Stanton L

出版信息

Nat Med. 2003 Sep;9(9):1109-10. doi: 10.1038/nm0903-1109.

DOI:10.1038/nm0903-1109

PMID:12949518

Abstract

摘要

相似文献

Akt helps stem cells heal the heart.

Nat Med. 2003 Sep;9(9):1109-10. doi: 10.1038/nm0903-1109.

Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts.经Akt修饰的间充质干细胞可预防梗死心脏的重塑并恢复其功能。

Nat Med. 2003 Sep;9(9):1195-201. doi: 10.1038/nm912. Epub 2003 Aug 10.

[Potential of adrenomedullin as a therapeutic tool for left ventricular remodeling after myocardial infarction].[肾上腺髓质素作为心肌梗死后左心室重塑治疗工具的潜力]

Nihon Rinsho. 2004 Sep;62 Suppl 9:302-6.

Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes.Akt的核靶向作用增强了心肌细胞的激酶活性和存活率。

Circ Res. 2004 Apr 16;94(7):884-91. doi: 10.1161/01.RES.0000124394.01180.BE. Epub 2004 Feb 26.

We think we see a pattern emerging here.我们认为我们在此处看到一种模式正在显现。

Circulation. 2005 Jan 18;111(2):120-1. doi: 10.1161/01.CIR.0000153622.49496.10.

Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.旁分泌作用是Akt修饰的间充质干细胞对缺血性心脏产生显著保护作用的原因。

Nat Med. 2005 Apr;11(4):367-8. doi: 10.1038/nm0405-367.

Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway.血管内皮生长因子通过 PI3K/Akt 通路促进心脏干细胞迁移。

Exp Cell Res. 2009 Dec 10;315(20):3521-31. doi: 10.1016/j.yexcr.2009.09.026. Epub 2009 Oct 2.

Cytoprotective effect of sodium orthovanadate on ischemia/reperfusion-induced injury in the rat heart involves Akt activation and inhibition of fodrin breakdown and apoptosis.原钒酸钠对大鼠心脏缺血/再灌注损伤的细胞保护作用涉及Akt激活以及对血影蛋白降解和细胞凋亡的抑制。

J Pharmacol Exp Ther. 2004 Dec;311(3):1249-55. doi: 10.1124/jpet.104.070839. Epub 2004 Aug 3.

Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.心脏干细胞和心肌细胞衰老、心力衰竭以及胰岛素样生长因子-1过表达。

Circ Res. 2004 Mar 5;94(4):514-24. doi: 10.1161/01.RES.0000117306.10142.50. Epub 2004 Jan 15.

Adrenomedullin infusion attenuates myocardial ischemia/reperfusion injury through the phosphatidylinositol 3-kinase/Akt-dependent pathway.肾上腺髓质素输注通过磷脂酰肌醇3-激酶/蛋白激酶B依赖性途径减轻心肌缺血/再灌注损伤。

Circulation. 2004 Jan 20;109(2):242-8. doi: 10.1161/01.CIR.0000109214.30211.7C. Epub 2003 Dec 22.

引用本文的文献

PEG hydrogel containing calcium-releasing particles and mesenchymal stromal cells promote vessel maturation.聚乙二醇水凝胶中含有释放钙离子的颗粒和间充质基质细胞，可促进血管成熟。

Acta Biomater. 2018 Feb;67:53-65. doi: 10.1016/j.actbio.2017.12.009. Epub 2017 Dec 13.

Myocardial AKT: the omnipresent nexus.心肌 AKT：无处不在的枢纽。

Physiol Rev. 2011 Jul;91(3):1023-70. doi: 10.1152/physrev.00024.2010.

Cardiac progenitor cell commitment is inhibited by nuclear Akt expression.核 Akt 表达抑制心脏祖细胞的定向分化。

Circ Res. 2011 Apr 15;108(8):960-70. doi: 10.1161/CIRCRESAHA.110.237156. Epub 2011 Feb 24.

Is endothelial progenitor cell dysfunction involved in altered angiogenic processes in patients with hypertension?内皮祖细胞功能障碍是否参与高血压患者血管生成过程的改变？

Curr Hypertens Rep. 2004 Feb;6(1):51-4. doi: 10.1007/s11906-004-0011-y.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验