Rho N-K, Youn S-J, Park H-S, Kim W-S, Lee E-S
Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Clin Exp Dermatol. 2003 Sep;28(5):502-3. doi: 10.1046/j.1365-2230.2003.01362.x.
Dystrophic cutaneous calcification may arise at sites of local trauma or in association with various disorders. Calcified nodules of the heel have been reported in high-risk neonates following repeated heel sticks to draw blood. We present a healthy 2-year-old boy with a calcified nodule on the heel secondary to a single heel stick in the neonatal period. The patient was born full-term at 38 weeks' gestation, with a birth weight appropriate for gestational age. A firm nodule was noticed at the age of 8 months; this became tender. Histology revealed epidermal and subepidermal deposition of calcium. Serum calcium and phosphate levels were normal. Although calcified heel nodules occur mostly in high-risk neonates, this case suggests that this condition also can occur in healthy children after only a single heel stick. Dermatologists should include this entity in the differential diagnosis of warty papules on the heels of children.
营养不良性皮肤钙化可能出现在局部创伤部位或与各种疾病相关。据报道，高危新生儿在反复足跟采血后足跟出现钙化结节。我们报告一例健康的2岁男孩，其足跟部的钙化结节继发于新生儿期单次足跟采血。患儿孕38周足月出生，出生体重与孕周相符。8个月大时发现一个质地坚硬的结节，该结节后来变得触痛。组织学检查显示表皮和表皮下有钙沉积。血清钙和磷水平正常。虽然钙化足跟结节大多发生在高危新生儿中，但该病例表明，这种情况在健康儿童单次足跟采血后也可能发生。皮肤科医生应将此病症纳入儿童足跟部疣状丘疹的鉴别诊断中。
