Steiner T J, Scher A I, Stewart W F, Kolodner K, Liberman J, Lipton R B
Division of Neuroscience, Imperial College London, London, UK, Neuroepidemiology Branch, NINDS/NIH, Bethesda, MD, USA.
Cephalalgia. 2003 Sep;23(7):519-27. doi: 10.1046/j.1468-2982.2003.00568.x.
This study estimates the 1-year prevalence of migraine in adults in England in relation to the major demographic variables of age, gender and ethnicity, and describes some of its features, including aspects of consequential disability. A telephone survey was conducted of a random sample (n = 4007) of the population aged 16-65 years of mainland England using a previously validated diagnostic interview. The response rate was 76.5%. Overall, 7.6% of males and 18.3% of females reported migraine with or without aura within the last year meeting diagnostic criteria closely approximate to those of the International Headache Society. Prevalence of migraine varied with age, rising through early adult life and declining in the late 40s and early 50s. Prevalence was higher in Caucasians than in other races. Attack rates were > or = 1/month in most migraineurs, and most experienced interference with daily activities in > or = 50% of their attacks. On average, an estimated 5.7 working days were lost per year for every working or student migraineur, although the most disabled 10% accounted for 85% of the total. Results were in keeping with those from surveys in other countries. If these findings in mainland England are projected to the entire UK population, we estimate that 5.85 million people aged 16-65 years experience 190 000 migraine attacks every day and lose 25 million days from work or school each year because of them. Migraine is an important public health problem in the UK, associated with very substantial costs.
本研究评估了英格兰成年人中偏头痛的1年患病率与年龄、性别和种族等主要人口统计学变量之间的关系，并描述了其一些特征，包括随之而来的残疾方面。使用先前经过验证的诊断性访谈，对英格兰大陆16 - 65岁人群的随机样本（n = 4007）进行了电话调查。应答率为76.5%。总体而言，在过去一年中，7.6%的男性和18.3%的女性报告患有伴或不伴先兆的偏头痛，其诊断标准与国际头痛协会的标准非常接近。偏头痛患病率随年龄变化，在成年早期上升，在40多岁后期和50岁初期下降。白种人的患病率高于其他种族。大多数偏头痛患者的发作频率≥1次/月，并且大多数患者在≥50%的发作中经历了对日常活动的干扰。平均而言，每位在职或学生偏头痛患者每年估计损失5.7个工作日，尽管最严重残疾的10%占总损失的85%。结果与其他国家的调查结果一致。如果将英格兰大陆的这些研究结果推算至整个英国人口，我们估计16 - 65岁的585万人每天经历19万次偏头痛发作，并且每年因偏头痛而损失2500万个工作日或学习日。偏头痛在英国是一个重要的公共卫生问题，伴有非常巨大的成本。
