树突状细胞与肠道细菌菌群：局部黏膜免疫反应的作用
Dendritic cells and the intestinal bacterial flora: a role for localized mucosal immune responses.
作者信息
Uhlig Holm H, Powrie Fiona
机构信息
Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
出版信息
J Clin Invest. 2003 Sep;112(5):648-51. doi: 10.1172/JCI19545.
Abstract
Mammals coexist in an overall symbiotic relationship with a complex array of commensal bacterial flora that colonizes the gastrointestinal tract. These intestinal bacteria interface with cells of the mucosal immune system, including DCs. Here we discuss mechanisms of interaction between intestinal bacteria and DCs and the role of localized gastrointestinal immune responses.
摘要
哺乳动物与定植于胃肠道的一系列复杂共生细菌菌群以整体共生关系共存。这些肠道细菌与包括树突状细胞（DCs）在内的黏膜免疫系统细胞相互作用。在此，我们讨论肠道细菌与树突状细胞之间的相互作用机制以及局部胃肠道免疫反应的作用。
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