Kurtz Joachim, Franz Karoline
Department of Evolutionary Ecology, Max Planck Institute of Limnology, August-Thienemann Strasse 2, 24306 Plön, Germany.
Nature. 2003 Sep 4;425(6953):37-8. doi: 10.1038/425037a.
Acquired immunity in vertebrates is characterized by immunological memory and specificity, whereas the innate defence systems of invertebrates are assumed to have no specific memory. Here we use a model system of a copepod, which is a minute crustacean, and a parasitic tapeworm to show that the success of reinfection depends on the antigenic resemblance between the consecutively encountered parasites. This finding indicates that an invertebrate defence system may be capable of specific memory.
脊椎动物的获得性免疫具有免疫记忆和特异性，而无脊椎动物的先天防御系统被认为没有特异性记忆。在此，我们使用一种桡足类动物（一种微小的甲壳类动物）和一种寄生绦虫的模型系统，来表明再次感染的成功与否取决于连续遇到的寄生虫之间的抗原相似性。这一发现表明，无脊椎动物的防御系统可能具有特异性记忆。
