Bamberg C, Laskowski J, Zimmermann R, Gross G
Klinik und Poliklinik für Dermatologie und Venerologie der Universität Rostock.
Hautarzt. 2003 Sep;54(9):864-8. doi: 10.1007/s00105-003-0525-2.
Minocycline is an effective treatment of acne vulgaris, especially for inflammatory forms. Prescription rates have increased in recent years accompanied by a number of reports concerning drug-induced side effects. An otherwise healthy woman developed an erythema multiform-like rash and and toxic hepatic damage causing cholestatic jaundice following long-term minocycline use. Unusual cutaneous lipid deposition also developed. Minocycline-induced side effects are reviewed.
米诺环素是寻常痤疮的一种有效治疗药物，尤其适用于炎症性痤疮。近年来，其处方率有所上升，同时也出现了一些关于药物不良反应的报道。一名原本健康的女性在长期使用米诺环素后出现了多形红斑样皮疹以及导致胆汁淤积性黄疸的中毒性肝损伤。还出现了罕见的皮肤脂质沉积。本文对米诺环素引起的不良反应进行了综述。
