Arslan Selcuk, Gökmen Oya, Tuncay Görkem
GOP, Rabat Sokak 19/3, Ankara, Turkey.
Arch Gynecol Obstet. 2004 Jul;270(1):31-3. doi: 10.1007/s00404-002-0471-8. Epub 2003 Aug 29.
The objective was to characterize postmenopausal women with endometrial polyps and to evaluate their significance.
The study population included all consecutive postmenopausal patients with a diagnosis of endometrial polyps. Demographic, medical and gynecological data were assessed with regard to the endometrial histologic findings.
Of the 181 eligible patients, 34 had endometrial hyperplasia (4 cases of them had endometrial carcinoma). The 144 patients using hormone replacement therapy had significantly higher rate of endometrial hyperplasia than non-hormone users (p<0.006). No differences were observed among the endometrial histological categories for any of the presenting symptoms and signs, ultrasonographic findings, or medical histories.
Postmenopausal endometrial polyps is a common, mostly benign entity. However, the relatively high rate of concomitant endometrial hyperplasia, especially in patients receiving hormone replacement therapy, dictates a thorough histological evaluation in all cases.
本研究旨在对绝经后子宫内膜息肉患者进行特征描述并评估其意义。
研究对象包括所有连续诊断为子宫内膜息肉的绝经后患者。收集患者的人口统计学、医学及妇科数据，并与子宫内膜组织学检查结果进行对照评估。
在181例符合条件的患者中，34例存在子宫内膜增生（其中4例患有子宫内膜癌）。使用激素替代疗法的144例患者子宫内膜增生发生率显著高于未使用激素者（p<0.006）。在任何症状体征、超声检查结果或病史方面，各子宫内膜组织学类别之间均未观察到差异。
绝经后子宫内膜息肉较为常见，大多为良性病变。然而，子宫内膜增生的发生率相对较高，尤其是在接受激素替代疗法的患者中，这表明所有病例均需进行全面的组织学评估。
