Orvieto R, Bar-Hava I, Dicker D, Bar J, Ben-Rafael Z, Neri A
Department of Obstetrics and Gynecology, Rabin Medical Center, Petah Tiqva, Israel.
Acta Obstet Gynecol Scand. 1999 Nov;78(10):883-6.
To characterize postmenopausal women with endometrial polyps and to evaluate their significance.
The study population included all consecutive postmenopausal patients with a diagnosis of endometrial polyp, treated at our center over a two-year period. Demographic, medical and gynecological data were assessed with regard to the endometrial histologic findings.
Of the 146 eligible patients, 15 had endometrial hyperplasia (four with atypia); there were no cases of endometrial carcinoma. The 20 patients (13.7%) using hormone replacement therapy had a significantly higher rate of endometrial hyperplasia than non-hormone users (p<0.006). No differences were observed among the endometrial histological categories for any of the presenting symptoms and signs, ultrasonographic findings, or medical histories.
Postmenopausal endometrial polyp is a common, mostly benign entity. However, the relatively high rate of concomitant endometrial hyperplasia, especially in patients receiving hormone replacement therapy, dictates a thorough histological evaluation in all cases.
对绝经后子宫内膜息肉患者进行特征描述并评估其意义。
研究人群包括在两年期间于本中心接受治疗的所有连续诊断为子宫内膜息肉的绝经后患者。根据子宫内膜组织学检查结果评估人口统计学、医学和妇科数据。
在146例符合条件的患者中，15例有子宫内膜增生（4例有异型增生）；无子宫内膜癌病例。使用激素替代疗法的20例患者（13.7%）的子宫内膜增生率显著高于未使用激素者（p<0.006）。在任何症状和体征、超声检查结果或病史方面，各子宫内膜组织学类别之间均未观察到差异。
绝经后子宫内膜息肉是一种常见的、大多为良性的病变。然而，伴随子宫内膜增生的发生率相对较高，尤其是在接受激素替代疗法的患者中，这决定了对所有病例都需要进行全面的组织学评估。
