Kerdvongbundit Varunee, Sirirat Mullika, Sirikulsathean Anongporn, Kasetsuwan Julalux, Hasegawa Akira
Department of Oral Medicine and Periodontics, Faculty of Dentistry, Mahidol University, 6 Yothi Street, Rachathavee, Payathai, Bangkok 10400, Thailand.
Odontology. 2002 Sep;90(1):52-6. doi: 10.1007/s102660200008.
The purpose of this study was to evaluate the microcirculation in subjects with moderate gingivitis, periodontitis, and healthy gingiva. Sixty adult volunteers with clinically healthy gingiva, moderate gingivitis, and periodontitis (20 subjects each) participated in this study. The ages of the research samples ranged from 20 to 35 years. Gingival health was evaluated by using the qualitative plaque index, gingival index, gingival bleeding index, tooth mobility, probing pocket depth, clinical attachment level, and laser Doppler flowmetry (LDF) on six maxillary anterior teeth. LDF data were recorded at the facial aspect of free gingivae, interdental gingivae, attached gingivae, and alveolar mucosae on six maxillary anterior teeth, utilizing an acrylic stent to stabilize the probe. This technique was then modified to circumvent contamination by saliva and gingival exudate. When results were compared at similar sites in each patient within a trial group, there were significant differences in blood flow measurements at all the sites examined between moderate gingivitis and periodontitis when compared with measurements in healthy human gingiva. However, blood flow measurements within the same group showed significant differences at every site, at P< 0.01.
本研究的目的是评估患有中度牙龈炎、牙周炎以及牙龈健康的受试者的微循环情况。六十名成年志愿者分别患有临床健康牙龈、中度牙龈炎和牙周炎（每组20名受试者）参与了本研究。研究样本的年龄范围为20至35岁。通过采用定性菌斑指数、牙龈指数、牙龈出血指数、牙齿松动度、探诊深度、临床附着水平以及对上颌六颗前牙进行激光多普勒血流仪（LDF）检测来评估牙龈健康状况。利用丙烯酸支架固定探头，在上颌六颗前牙的游离龈、龈乳头、附着龈和牙槽黏膜的面部记录LDF数据。随后对该技术进行了改进，以避免唾液和牙龈渗出物的污染。当在试验组内的每位患者的相似部位比较结果时，与健康人牙龈的测量值相比，中度牙龈炎和牙周炎患者在所有检查部位的血流测量值存在显著差异。然而，同一组内的血流测量值在每个部位均显示出显著差异，P<0.01。
