van den Heuvel Marcel
MRC Functional Genetics Unit, Department of Human Anatomy and Genetics, University of Oxford, South Parks Road, OX1 3QX, Oxford, UK.
Curr Biol. 2003 Sep 2;13(17):R686-8. doi: 10.1016/s0960-9822(03)00610-9.
Many cell signalling pathways are modulated in important ways by general cellular machineries, such as those mediating protein degradation and translocation. Two recent studies have revealed roles for such mechanisms in the Hedgehog signalling pathway in Drosophila.
许多细胞信号通路受到一般细胞机制的重要调节，例如那些介导蛋白质降解和转运的机制。最近的两项研究揭示了这些机制在果蝇的刺猬信号通路中的作用。
