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酒精性肝病中的肝脏铁过载:为何会发生以及其在发病机制中的作用是什么?

Hepatic iron overload in alcoholic liver disease: why does it occur and what is its role in pathogenesis?

作者信息

Rouault Tracey A

机构信息

Section on Human Iron Metabolism, Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, Building 18, Room 101, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Alcohol. 2003 Jun;30(2):103-6. doi: 10.1016/s0741-8329(03)00102-2.

Abstract

Iron overload is frequently observed in alcoholic liver disease. However, it is not known why hepatic iron accumulation occurs or how it contributes to disease progression. In this review, information about the role of iron in the pathophysiology of liver disease is reviewed and discussed.

摘要

铁过载在酒精性肝病中经常被观察到。然而,尚不清楚肝脏铁蓄积为何会发生,以及它如何促进疾病进展。在这篇综述中,我们对铁在肝病病理生理学中的作用的相关信息进行了综述和讨论。

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