Martins Claudia A, Alvito Paula, Tavares Maria João, Pereira Paulo, Doucette Gregory, Franca Susana
Laboratório de Microbiologia e Ecotoxicologia, Instituto Nacional de Saúde Dr. Ricardo Jorge, 1649-016 Lisbon, Portugal.
Appl Environ Microbiol. 2003 Sep;69(9):5693-8. doi: 10.1128/AEM.69.9.5693-5698.2003.
Paralytic shellfish toxins (PSTs) are potent neurotoxins produced by certain dinoflagellate and cyanobacterial species. The autonomous production of PSTs by bacteria remains controversial. In this study, PST production by two bacterial strains, isolated previously from toxic dinoflagellates, was evaluated using biological and analytical methods. Analyses were performed under conditions determined previously to be optimal for toxin production and detection. Our data are inconsistent with autonomous bacterial PST production under these conditions, thereby challenging previous findings for the same strains.
麻痹性贝类毒素(PSTs)是由某些甲藻和蓝藻物种产生的强效神经毒素。细菌自主产生PSTs仍存在争议。在本研究中,使用生物学和分析方法评估了先前从有毒甲藻中分离出的两种细菌菌株产生PSTs的情况。分析是在先前确定的毒素产生和检测最佳条件下进行的。我们的数据与这些条件下细菌自主产生PSTs的情况不一致,从而对同一菌株先前的研究结果提出了质疑。