Vance M L, Hartman M L, Thorner M O
Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville 22908.
Horm Res. 1992;38 Suppl 1:85-8. doi: 10.1159/000182577.
The regulation of growth hormone (GH) secretion in humans is a complex process which comprises more than stimulation by GH-releasing hormone and suppression by somatostatin. Although these two hypothalamic hormones are the primary regulators of GH secretion, they most likely function as the final pathway through which numerous factors influence GH synthesis and secretion. Some of the modulators of GH secretion include neurotransmitters, circulating glucose, insulin-like growth factor I and gonadal steroid concentrations. Age, nutrition and body composition are also related to the amount and pattern of GH secretion in humans. The influence of nutritional status on GH secretion is becoming more clearly defined.
人类生长激素（GH）分泌的调节是一个复杂的过程，它不仅仅包括生长激素释放激素的刺激和生长抑素的抑制。尽管这两种下丘脑激素是GH分泌的主要调节因子，但它们很可能是众多因素影响GH合成和分泌的最终途径。GH分泌的一些调节因子包括神经递质、循环葡萄糖、胰岛素样生长因子I和性腺类固醇浓度。年龄、营养和身体组成也与人类GH分泌的量和模式有关。营养状况对GH分泌的影响正变得越来越清晰。
