Eichner H, Eichner V, Münzel M, Hochstrasser K
Laryngol Rhinol Otol (Stuttg). 1975 Jul;54(7):554-65.
Parotid saliva was collected in 10-minutes-fractions during rest and stimulation from 66 healthy individuals. The time of collection was 80 minutes, in every sample flow-rate, total-protein-concentration, IgA- and Lysozyme-content were determined. According to sex and age of the individuals, the results obtained were classified in four groups. Stimulation produced characteristic changes in the flow-rates, which seemed to be correlated with the age of the persons. The total-protein-concentration of the single samples showed great differences; yet, regarding flow-rate and proteinconcentration together, the so calculated secretion of protein of every gland was almost the same. Secretion of IgA was dependent on age and sex: the secretion-rate was greater in females than in males. Besides, younger people had lower IgA-concentrations than older ones. On the other hand, lysozyme-secretion was reciprocal to IgA-secretion. The concentration of lysozyme was much higher in young persons compared with the older group. The clinical importance of this findings is discussed.
在休息和刺激期间，从66名健康个体中每隔10分钟收集一次腮腺唾液。收集时间为80分钟，测定每个样本的流速、总蛋白浓度、IgA和溶菌酶含量。根据个体的性别和年龄，将所得结果分为四组。刺激使流速产生了特征性变化，这似乎与个体年龄相关。单个样本的总蛋白浓度差异很大；然而，综合流速和蛋白浓度来看，每个腺体如此计算出的蛋白分泌量几乎相同。IgA的分泌取决于年龄和性别：女性的分泌率高于男性。此外，年轻人的IgA浓度低于年长者。另一方面，溶菌酶的分泌与IgA的分泌相反。年轻人组的溶菌酶浓度比年长者组高得多。本文讨论了这一发现的临床意义。
