El-Hamamsy Ismaïl, Dürrleman Nicolas, Stevens Louis Mathieu, Leung Tack Ki, Theoret Sylvie, Carrier Michel, Perrault Louis P
Research Center and Department of Cardiovascular Surgery, Montreal, Quebec, Canada
Ann Thorac Surg. 2003 Sep;76(3):801-4. doi: 10.1016/s0003-4975(03)00725-2.
Radial artery infections secondary to catheterization for blood pressure monitoring are rare but potentially serious complications. The objective of the study was to evaluate the incidence, the risk factors and the evolution of radial artery infections following cardiac surgery.
A retrospective review of 8300 patients undergoing cardiac surgery between 1998 and 2002 at the Montreal Heart Institute (MHI) was undertaken. All patients with superficial radial artery infections, infected radial artery pseudoaneurysms, and arterial catheter-related bacteremia were considered using prospective global surveillance of all nosocomial infections over the study period by an infection control nurse.
Thirteen patients with radial infections were encountered (0.2%) with bacteremia occurring in 9 patients (0.15%). Five patients developed infected radial artery pseudoaneurysms (0.05%) and 5 patients developed subsequent sternal wound infections. Two patients died in their early postoperative evolution. Mean patient age was 67 years old and mean duration of cannulation was 5.8 days. Only 1 patient had diabetes. Seven of 13 patients were positive for Staphylococcus aureus (54%). All patients had undergone cardiopulmonary bypass (CPB) for various procedures. All superficial infections responded well to antibiotic therapy. Early surgical intervention is essential in cases of infected radial artery pseudoaneurysms.
The postoperative state and cardiopulmonary bypass put patients at risk for infectious complications. Strict systematic changing of arterial lines on a timely basis is unwarranted in our opinion. A high suspicion index, aggressive surgical treatment of bacterial arteritis and appropriate intravenous antibiotics are essential to improve the prognosis.
因血压监测进行桡动脉置管继发的感染罕见但可能是严重并发症。本研究的目的是评估心脏手术后桡动脉感染的发生率、危险因素及病情演变。
对1998年至2002年在蒙特利尔心脏研究所(MHI)接受心脏手术的8300例患者进行回顾性研究。在研究期间,感染控制护士对所有医院感染进行前瞻性全面监测,将所有浅表桡动脉感染、感染性桡动脉假性动脉瘤及动脉导管相关菌血症患者纳入研究。
共发现13例桡动脉感染患者(0.2%),9例发生菌血症(0.15%)。5例患者出现感染性桡动脉假性动脉瘤(0.05%),5例患者随后发生胸骨伤口感染。2例患者在术后早期死亡。患者平均年龄67岁,平均置管时间5.8天。仅1例患者患有糖尿病。13例患者中有7例金黄色葡萄球菌检测呈阳性(54%)。所有患者均因各种手术接受了体外循环(CPB)。所有浅表感染对抗生素治疗反应良好。对于感染性桡动脉假性动脉瘤病例,早期手术干预至关重要。
术后状态及体外循环使患者面临感染并发症风险。我们认为,没有必要严格定期及时更换动脉导管。高度怀疑指数、积极手术治疗细菌性动脉炎及适当的静脉抗生素治疗对于改善预后至关重要。