Bearden Thomas S, Cassisi Jeffrey E, Pineda Mario
Jackson State University, Jackson, Mississippi, USA.
Appl Psychophysiol Biofeedback. 2003 Sep;28(3):241-53. doi: 10.1023/a:1024689315563.
One year after a left posterior and thalamic stroke, a 52-year-old male participant was treated with 14 weeks of theta reduction neurofeedback training. Imaging studies revealed left temporal, parietal, occipital, and bilateral thalamic infarctions along the distribution of the posterior cerebral artery. Neuropsychological testing demonstrated severe verbal memory, naming, visual tracking, and fine motor deficits. Additionally, alexia without agraphia was present. A pretraining quantitative electroencephalograph (QEEG) found alpha attenuation, lack of alpha reactivity to eye opening, and excessive theta activity from the left posterior head region. Neurofeedback training to inhibit 4-8 Hz theta activity was conducted for 42 sessions from left hemisphere sites. Over the course of the training, significant reductions in theta amplitude occurred from the training sites as assessed from the post-session baseline periods. Posttraining, a relative normalization of the QEEG was observed from the left posterior head region.
一名52岁男性参与者在左侧丘脑后部中风一年后，接受了为期14周的θ波减少神经反馈训练。影像学研究显示，沿大脑后动脉分布区域存在左侧颞叶、顶叶、枕叶及双侧丘脑梗死。神经心理学测试表明，该患者存在严重的言语记忆、命名、视觉追踪及精细运动功能缺陷。此外，还存在失读不伴失写症。训练前的定量脑电图（QEEG）发现，患者存在α波衰减、对睁眼缺乏α波反应性，以及左侧后头部区域θ波活动过度。从左侧半球部位进行了42次抑制4 - 8Hz θ波活动的神经反馈训练。在训练过程中，根据训练后阶段的基线期评估，训练部位的θ波振幅显著降低。训练后，观察到左侧后头部区域的QEEG相对恢复正常。
