Urata M, Isomoto H, Murase K, Wada A, Yanagihara K, Hirakata Y, Takeshima F, Omagari K, Mizuta Y, Murata I, Kohno S
Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan.
J Int Med Res. 2003 Jul-Aug;31(4):299-306. doi: 10.1177/147323000303100407.
The microbicidal activities of superoxidized water (electrolysed strong acid water [ESAW] or electrolysed weak acid water [EWAW]), ozonated water, 0.05% chlorhexidine and 2% glutaraldehyde were tested against seven strains of clinical micro-organism isolates. Following incubation of bacterial suspensions in ESAW and EWAW for 10 s, the number of micro-organisms was reduced below the detection limit. The microbicidal activities of ESAW and EWAW were similar to that of glutaraldehyde, and superior to ozonated water and 0.05% chlorhexidine. The microbicidal activities of ESAW, EWAW and ozonated water were markedly diminished in the presence of albumin. Microbial contamination of upper gastrointestinal endoscopes was detected after 90 endoscopic procedures, but treatment of the endoscope with ESAW, EWAW or ozonated water eradicated the microbes. These results indicate that ESAW and EWAW are effective disinfectants after mechanical cleaning of upper gastrointestinal endoscopes, and can, therefore, be used in the endoscopy unit.
测试了超氧化水（电解强酸水[ESAW]或电解弱酸水[EWAW]）、臭氧水、0.05%氯己定和2%戊二醛对7株临床微生物分离株的杀菌活性。将细菌悬液在ESAW和EWAW中孵育10秒后，微生物数量减少至检测限以下。ESAW和EWAW的杀菌活性与戊二醛相似，优于臭氧水和0.05%氯己定。在白蛋白存在的情况下，ESAW、EWAW和臭氧水的杀菌活性显著降低。90例内镜检查后检测到上消化道内镜存在微生物污染，但用ESAW、EWAW或臭氧水处理内镜可根除微生物。这些结果表明，ESAW和EWAW在上消化道内镜机械清洗后是有效的消毒剂，因此可在内镜检查科室使用。
