Karanes Chatchada, Confer Dennis, Walker Tim, Askren Andrea, Keller Claire
National Marrow Donor Program (NMDP), Minneapolis, Minnesota, USA.
Oncology (Williston Park). 2003 Aug;17(8):1036-8, 1043-4, 1164-7.
Since its founding in 1986, the NMDP has facilitated more than 16,000 transplants for patients with blood disorders such as leukemia and aplastic anemia, as well as immune system disorders and genetic disorders. The donors who provided the blood stem cells for these transplants came from the NMDP Registry, the world's largest and most diverse registry of potential blood stem cell donors. Initiating a search of the NMDP Registry for an HLA-matched unrelated donor is as simple as submitting to the NMDP a patient's HLA typing results along with basic demographic and disease information. If a suitable donor is identified, the NMDP coordinates the steps needed to bring the donated stem cells--whether they be marrow, PBSC, or cord blood--to a patient. After reading this article, physicians should have a greater understanding of the complicated process needed to bring about an unrelated donor stem cell transplant. A better understanding of the role the NMDP plays in unrelated donor stem cell transplantation reduces the chances that physicians and patients will have unrealistic expectations about the process. To initiate a preliminary search of the NMDP Registry, contact the NMDP Office of Patient Advocacy toll-free at 1-888-999-6743. A preliminary search reqest form can also be submitted via the NMDP website:www.marrow.org
自1986年成立以来，国家骨髓捐赠项目（NMDP）已为患有白血病和再生障碍性贫血等血液疾病以及免疫系统疾病和遗传疾病的患者促成了16000多例移植手术。为这些移植手术提供血液干细胞的捐赠者来自NMDP登记库，这是世界上最大、最多样化的潜在血液干细胞捐赠者登记库。在NMDP登记库中搜索HLA匹配的无关供体，只需向NMDP提交患者的HLA分型结果以及基本人口统计学和疾病信息即可。如果找到合适的供体，NMDP会协调将捐赠的干细胞（无论是骨髓、外周血干细胞还是脐带血）送到患者手中所需的步骤。阅读本文后，医生应该对进行无关供体干细胞移植所需的复杂过程有更深入的了解。更好地理解NMDP在无关供体干细胞移植中所起的作用，可减少医生和患者对该过程抱有不切实际期望的可能性。要在NMDP登记库中进行初步搜索，请拨打免费电话1-888-999-6743联系NMDP患者权益办公室。也可以通过NMDP网站：www.marrow.org提交初步搜索请求表。
