Chen Aimin, Rogan Walter J
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA.
Emerg Infect Dis. 2003 Aug;9(8):960-4. doi: 10.3201/eid0908.030082.
Although dichlorodiphenyl trichloroethane (DDT) is being banned worldwide, countries in sub-Saharan Africa have sought exemptions for malaria control. Few studies show illness in children from the use of DDT, and the possibility of risks to them from DDT use has been minimized. However, plausible if inconclusive studies associate DDT with more preterm births and shorter duration of lactation, which raise the possibility that DDT does indeed have such toxicity. Assuming that these associations are causal, we estimated the increase in infant deaths that might result from DDT spraying. The estimated increases are of the same order of magnitude as the decreases from effective malaria control. Unintended consequences of DDT use need to be part of the discussion of modern vector control policy.
尽管滴滴涕（DDT）在全球范围内被禁用，但撒哈拉以南非洲国家寻求豁免以用于疟疾防治。很少有研究表明儿童因使用滴滴涕而患病，并且使用滴滴涕给他们带来风险的可能性已降至最低。然而，虽然尚无定论，但有看似合理的研究将滴滴涕与更多早产和更短哺乳期联系起来，这增加了滴滴涕确实具有此类毒性的可能性。假设这些关联是因果关系，我们估算了喷洒滴滴涕可能导致的婴儿死亡增加数。估算的增加数与有效疟疾防治导致的减少数处于同一数量级。使用滴滴涕的意外后果需要成为现代病媒控制政策讨论的一部分。
