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在使用滴滴涕控制疟疾后,夸祖鲁母亲母乳中滴滴涕及其代谢物的含量。

Levels of DDT and metabolites in breast milk from Kwa-Zulu mothers after DDT application for malaria control.

作者信息

Bouwman H, Cooppan R M, Reinecke A J, Becker P J

机构信息

Department of Zoology, Potchefstroom University for CHE, Republic of South Africa.

出版信息

Bull World Health Organ. 1990;68(6):761-8.

Abstract

Concentrations of DDT, DDE and DDD were determined in the breast milk of Kwa-Zulu mothers residing in two different areas--with and without annual intra-domiciliary applications of DDT for the interruption of malaria transmission (exposed and control groups, respectively). While no significant change in levels with time was found in the control group, both DDT and DDE in breast milk of the exposed group increased after DDT application and this continued for three more months, after which it did not decrease appreciably. Percentage DDT increased from 42.57% (sigma DDT = 12.21 mg/kg milk fat) before spraying to 50.87% (sigma DDT = 13.79 mg/kg milk fat) following DDT application. At 6 and 9 months after the application it was 45.85% (sigma DDT = 19.49 mg/kg milk fat) and 43.27% (sigma DDT = 18.34 mg/kg milk fat), respectively. These results suggest a risk to the health of the infants in the exposed group.

摘要

对居住在夸祖鲁两个不同地区的母亲的母乳中滴滴涕(DDT)、滴滴伊(DDE)和滴滴滴(DDD)浓度进行了测定,这两个地区分别为每年在室内使用滴滴涕以阻断疟疾传播的地区(暴露组)和未使用的地区(对照组)。对照组中,母乳中这些物质的含量随时间未出现显著变化,而暴露组母乳中的滴滴涕和滴滴伊在使用滴滴涕后均有所增加,且持续了三个月,之后也未明显下降。喷洒前,滴滴涕占总含量的百分比为42.57%(总滴滴涕含量为12.21毫克/千克乳脂),使用滴滴涕后升至50.87%(总滴滴涕含量为13.79毫克/千克乳脂)。使用滴滴涕6个月和9个月后,该百分比分别为45.85%(总滴滴涕含量为19.49毫克/千克乳脂)和43.27%(总滴滴涕含量为18.34毫克/千克乳脂)。这些结果表明暴露组婴儿的健康存在风险。

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本文引用的文献

1
DDT AND DDE IN THE BODY FAT OF PEOPLE IN ISRAEL.以色列人体内脂肪中的滴滴涕和滴滴伊
Arch Environ Health. 1965 Sep;11:375-9. doi: 10.1080/00039896.1965.10664233.
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Chemical contaminants in human milk.人乳中的化学污染物。
Residue Rev. 1983;89:1-128. doi: 10.1007/978-1-4612-5601-4_1.
7
DDT residues in human milk from New Guinea natives.新几内亚当地居民母乳中的滴滴涕残留量。
Med J Aust. 1972 Jun 17;1(25):1297-300. doi: 10.5694/j.1326-5377.1972.tb116496.x.

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