Danić Davorin, Danić Ana
Department of Otorhinolaryngology and Cervicofacial Surgery, Dr. Josip Bencević General Hospital, 35000 Slavonski Brod, Croatia.
Acta Dermatovenerol Croat. 2003;11(3):153-7.
Cutaneous metastases from carcinoma are relatively uncommon in clinical practice. Metastasis to skin sites from squamous cell carcinoma of the mucosa of the head and neck are also very rare. However, skin metastases may be the first clinical evidence of the malignant disease or its loco-regional recurrence. Early recognition of skin metastasis can lead to an accurate and prompt diagnosis and timely treatment. Patients with skin metastases have very poor prognosis. We report on four such patients, one of them with multiple skin metastases from the squamous cell carcinoma in the cervical part of the esophagus above and below the level of the diaphragm. In reviewing the literature, only two cases of solitary skin metastases below the diaphragm from laryngeal squamous cell carcinomas have been reported
在临床实践中，癌的皮肤转移相对不常见。头颈部黏膜鳞状细胞癌转移至皮肤部位的情况也非常罕见。然而，皮肤转移可能是恶性疾病或其局部区域复发的首个临床证据。早期识别皮肤转移可实现准确、迅速的诊断及及时治疗。发生皮肤转移的患者预后很差。我们报告了4例这样的患者，其中1例在食管颈段有多个皮肤转移灶，位于膈肌上下，是鳞状细胞癌。在查阅文献时，仅报道过2例喉鳞状细胞癌在膈肌以下出现孤立性皮肤转移的病例
