[多聚甲醛片在巴西医疗机构中的抗菌活性及其使用条件再现]

[Antimicrobial activity of paraformaldehyde tablets reproducing their use conditions in Brazilian health institutions].

作者信息

Graziano Kazuko Uchikawa, Figueiredo Luciene

机构信息

Departamento de Enfermagem Médico-Cirúrgica, Escola de Enfermagem, Universidade de São Paulo.

出版信息

Rev Esc Enferm USP. 2003 Mar;37(1):90-6. doi: 10.1590/s0080-62342003000100011.

DOI:10.1590/s0080-62342003000100011

PMID:12968434

Abstract

The sterilizing activity of Parafolmaldehyde Tablets reproducing the conditions of use in the Brazilian health Institutions (without the heating, without increment of the relative humidity, in 0.5%, even for a long period of exhibition of 12 hours) was evaluated "in vitro" by microbiologic monitoring, according to the methodology of the AOAC, officially adopted by the Brazilian Health Ministry for registration of that category of products. The results of the experiments refuted the sterilizing action of Parafolmaldehyde Tablets in this conditions. Thus, it was evaluated the disinfectant action of the product using the vegetative bacteria by Use Dilution Method, preconized for AOAC and adapted for gaseous products, against the tests microorganisms standardized Staphylococcus aureus (ATCCn. 6538), Samonella choleraesuis (ATCCn. 10708) and Pseudomonas aeruginosa (ATCC n. 15442). In these experiments, the results of the cultures showed 100% negative against all the tested bacteria inferring indications of disinfectant activity of high level action.

摘要

按照巴西卫生部正式采用的美国官方分析化学师协会（AOAC）方法，通过微生物监测“体外”评估了多聚甲醛片在模拟巴西医疗机构使用条件下（不加热、不增加相对湿度、浓度为0.5%、即使长时间暴露12小时）的杀菌活性。实验结果反驳了多聚甲醛片在此条件下的杀菌作用。因此，采用AOAC推荐并适用于气态产品的使用稀释法，使用营养细菌评估了该产品对标准测试微生物金黄色葡萄球菌（ATCC编号6538）、猪霍乱沙门氏菌（ATCC编号10708）和铜绿假单胞菌（ATCC编号15442）的消毒作用。在这些实验中，培养结果显示对所有测试细菌的杀灭率为100%，表明该产品具有高水平消毒活性。