Yao Qingwei, Kinney Elizabeth P, Yang Zhi
Department of Chemistry and Biochemistry, The Michael Faraday Laboratories, Northern Illinois University, DeKalb, Illinois 60115-2862, USA.
J Org Chem. 2003 Sep 19;68(19):7528-31. doi: 10.1021/jo034646w.
Palladium acetate was shown to be an extremely active catalyst for the Heck reaction of aryl bromides. Both the base and the solvent were found to have a fundamental influence on the efficiency of the reaction, with K(3)PO(4) and N,N-dimethylacetamide being the optimal base and solvent, respectively.
