钯(II)催化通过 Fujiwara-Moritani 反应的环状烯胺酮的脱氢烯基化反应。
Palladium(II)-catalyzed dehydrogenative alkenylation of cyclic enaminones via the Fujiwara-Moritani reaction.
机构信息
Department of Chemistry, University of Minnesota, 717 Delaware Street SE, Minneapolis, Minnesota 55414, USA.
出版信息
Org Lett. 2011 Nov 4;13(21):5932-5. doi: 10.1021/ol202677g. Epub 2011 Oct 13.
Abstract
A new Pd(II)-catalyzed dehydrogenative alkenylation reaction involving two alkenes was developed. A variety of nonaromatic, cyclic enaminones were successfully coupled to primary and secondary alkenes yielding a series of unique 1,3-dienes. The generality of this transformation presents a useful strategy for directly cross-coupling alkenes and offers an attractive new approach to functionalize enaminones.
摘要
发展了一种新型 Pd(II)催化的脱氢烯基化反应，涉及两种烯烃。各种非芳族、环状烯胺酮成功地与一级和二级烯烃偶联，生成了一系列独特的 1,3-二烯。这种转化的通用性为直接交叉偶联烯烃提供了一种有用的策略，并为烯胺酮的功能化提供了一种有吸引力的新方法。
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