Lee W S, Veerasingam P D, Goh A Y T, Chua K B
Departments of Paediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia.
J Paediatr Child Health. 2003 Sep-Oct;39(7):518-22. doi: 10.1046/j.1440-1754.2003.00206.x.
To determine the epidemiology of rotavirus gastroenteritis in children admitted to an urban hospital in a developing country from South-East Asia.
Retrospective review of cases of acute gastroenteritis admitted to the children's ward of the University of Malaya Medical Centre, Kuala Lumpur, Malaysia, between 1996 and 1999.
During the study period, 333 cases (24%) of 1362 stool samples, obtained from children admitted with acute diarrhoea, were positive for rotavirus. Acute gastroenteritis constituted 8.2%, and rotavirus infection 1.6% of all the paediatric admissions each year. Of the 271 cases analysed, 72% of the affected population were less than 2 years of age. Peak incidence of admissions was between January to March, and September to October. Dehydration was common (92%) but electrolyte disturbances, lactose intolerance (5.2%), prolonged diarrhoea (2.6%) and cow's milk protein intolerance was uncommon. No deaths were recorded.
Rotavirus infection was a common cause of childhood diarrhoea that required hospital admission in an urban setting in Malaysia.
确定东南亚一个发展中国家城市医院收治的儿童轮状病毒肠胃炎的流行病学情况。
回顾性分析1996年至1999年间马来西亚吉隆坡马来亚大学医学中心儿童病房收治的急性肠胃炎病例。
在研究期间,从因急性腹泻入院的儿童中获取的1362份粪便样本中,有333例(24%)轮状病毒检测呈阳性。急性肠胃炎占每年所有儿科住院病例的8.2%,轮状病毒感染占1.6%。在分析的271例病例中,72%的受影响人群年龄小于2岁。入院高峰发生在1月至3月以及9月至10月。脱水情况常见(92%),但电解质紊乱、乳糖不耐受(5.2%)、持续性腹泻(2.6%)和牛奶蛋白不耐受情况不常见。无死亡病例记录。
在马来西亚城市地区,轮状病毒感染是导致儿童腹泻并需住院治疗的常见原因。