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评估一所监狱外展诊所对丙型肝炎的诊断和预防工作:对国家战略的启示

Evaluation of a prison outreach clinic for the diagnosis and prevention of hepatitis C: implications for the national strategy.

作者信息

Skipper C, Guy J M, Parkes J, Roderick P, Rosenberg W M

机构信息

HMP Parkhurst, Isle of Wight, UK.

出版信息

Gut. 2003 Oct;52(10):1500-4. doi: 10.1136/gut.52.10.1500.

DOI:10.1136/gut.52.10.1500
PMID:12970145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1773842/
Abstract

BACKGROUND

Hepatitis C virus (HCV) infection is a major public health problem recognised by the UK National Strategy that proposes that a care pathway for assessment, diagnosis, and treatment be established in all prisons, integrated within managed clinical networks. A prison sentence provides the opportunity to focus on traditionally hard to reach patients.

AIMS

To evaluate the prevalence of HCV infection in a UK prison cluster and to assess the effectiveness of a prison outreach service for hepatitis C.

SUBJECTS

Male prisoners.

METHODS

A nurse specialist led clinic within a cluster of adult prisons was established, offering health education on hepatitis C, advice on harm minimisation, and HCV testing. Infected prisoners were offered access to a care pathway leading to treatment. Outcome measures were uptake of the service, and diagnosis and treatment of hepatitis C.

RESULTS

A total of 8.5% of 1618 prisoners accepted testing: 30% had active infection with HCV. Most were ineligible for treatment due to psychiatric illness or did not receive treatment for logistic reasons. Injecting drug use was the major risk factor in all cases. Only 7% of HCV polymerase chain amplification positive inmates received treatment in prison.

CONCLUSION

There is a large pool of HCV infected prisoners at risk of complications, constituting a source of infection during their sentence and after discharge. A prison outreach clinic and care pathway was perceived as effective in delivering health education, reducing the burden on prison and hospital services. It provided an opportunity for intervention but had a limited effect in eradicating HCV in prisoners and it remains unclear how this might be achieved.

摘要

背景

丙型肝炎病毒(HCV)感染是英国国家战略所认可的一个主要公共卫生问题,该战略提议在所有监狱建立评估、诊断和治疗的护理路径,并将其整合到管理型临床网络中。监禁判决为关注传统上难以接触到的患者提供了机会。

目的

评估英国监狱群体中HCV感染的患病率,并评估监狱丙型肝炎外展服务的有效性。

研究对象

男性囚犯。

方法

在一组成人监狱内设立了一个由护士专家主导的诊所,提供丙型肝炎健康教育、危害最小化建议以及HCV检测。为感染的囚犯提供通向治疗的护理路径。结果指标包括服务的接受情况以及丙型肝炎的诊断和治疗情况。

结果

1618名囚犯中有8.5%接受了检测:30%有HCV活动性感染。大多数人由于精神疾病不符合治疗条件或因后勤原因未接受治疗。在所有病例中,注射吸毒是主要危险因素。HCV聚合酶链扩增阳性的囚犯中只有7%在监狱接受了治疗。

结论

有大量感染HCV的囚犯面临并发症风险,在服刑期间及出狱后构成传染源。监狱外展诊所和护理路径被认为在提供健康教育、减轻监狱和医院服务负担方面是有效的。它提供了干预机会,但在根除囚犯中的HCV方面效果有限,目前尚不清楚如何才能实现这一目标。

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