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[白色念珠菌对免疫功能紊乱儿童颊黏膜细胞的体外黏附性]

[Adherence in vitro of Candida albicans to cheek mucous membrane cells in children with immune disorders].

作者信息

Macura A B, Sysło J, Filip E

机构信息

Instytut Mikrobiologii AM, Krakowie.

出版信息

Med Dosw Mikrobiol. 1992;44(1-2):69-74.

PMID:1297038
Abstract

Evaluation regarded adherence of a strain of Candida albicans to epithelium of cheek mucous membrane, obtained from 31 children aged between one and 14 years with disturbance of immunity and from 10 healthy children. All children were tested immunologically by determination of total leukocytosis, granulocytosis, absolute lymphocytosis, active and total rosette tests, spontaneous and stimulated nitroblue-tetrazolium (NBT) tests and immunoglobulin A, G and M levels in serum. Adherence of C. albicans in vitro of epithelial cells of cheek mucous membrane was significantly higher in children with disturbance of immunity as compared with healthy control group (p < 0.001).

摘要

评估了从31名1至14岁免疫功能紊乱儿童和10名健康儿童获取的白色念珠菌菌株对颊粘膜上皮的黏附情况。所有儿童均通过检测全白细胞增多、粒细胞增多、绝对淋巴细胞增多、活性和总玫瑰花结试验、自发和刺激后的硝基蓝四氮唑(NBT)试验以及血清中免疫球蛋白A、G和M水平进行免疫检测。与健康对照组相比,免疫功能紊乱儿童颊粘膜上皮细胞体外白色念珠菌的黏附明显更高(p < 0.001)。

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